Platelet Rich Fibrin (PRF)/Growth Factors
Faster, Natural Healing With PRF Growth Factor Therapy in Los Angeles
After oral surgery, the quality and speed of your recovery matters. Whether you are healing from a tooth extraction, wisdom tooth removal, or bone grafting in preparation for implants, your body’s own biology plays the central role in how well you heal. Platelet Rich Fibrin (PRF) is a regenerative therapy that concentrates your body’s natural healing components and applies them directly to the surgical site, potentially reducing discomfort, shortening recovery time, and supporting stronger tissue and bone regeneration.
At Wilshire Oral Surgery and Implant Center, our surgeons Dr. Jonathan R. Shadi and Dr. Saman Vahedi offer PRF as an adjunct to oral surgical procedures for patients who want to support their healing naturally. Dr. Vahedi is a Board-Certified Oral and Maxillofacial Surgeon with advanced residency training from the University of Nebraska Medical Center, and both surgeons have extensive experience incorporating evidence-based regenerative techniques into patient care.
What Is Platelet Rich Fibrin (PRF)?
PRF is a concentration of your own blood’s healing components, including platelets, growth factors, white blood cells, and fibrin. First developed in France by Dr. Choukroun and refined over the past two decades, PRF has become one of the most studied regenerative tools in oral and maxillofacial surgery. Unlike PRP (platelet-rich plasma), PRF does not require any anticoagulants or additives. It is 100% autologous, meaning it comes entirely from your own blood.
| PRF | PRP | |
|---|---|---|
| Additives | None — 100% from your blood | Requires anticoagulants |
| Growth Factor Release | Slow, sustained 7–10 days | Rapid, shorter duration |
| Structure | Fibrin scaffold — acts as a membrane | Liquid or gel form |
| Best Used For | Oral surgery, bone regeneration, implants | Orthopedics, sports medicine, aesthetics |
| Rejection Risk | Virtually zero | Virtually zero |
How PRF Works
The PRF process is simple and performed right in our office as part of your surgical appointment. There are no special preparations or additional visits required.
A small sample of your blood is drawn, similar to a routine lab test. No special prep is needed.
Your blood is spun in a centrifuge to separate the fibrin-rich layer that contains concentrated platelets and growth factors.
The PRF membrane is placed directly into the surgical site, acting as a natural scaffold that gradually releases growth factors during the critical healing window.
The fibrin matrix in PRF acts similarly to a biological bandage, protecting the surgical site while slowly releasing growth factors over the following days. Because your blood is not chemically altered in any way, your body accepts and uses the PRF naturally, supporting healing from the inside out.
Benefits of PRF in Oral Surgery
PRF therapy can offer several advantages when incorporated into your oral surgical procedure.
Accelerates tissue regeneration and soft tissue healing around teeth and implants.
Reduces post-operative swelling and inflammation for a more comfortable recovery.
Supports a cleaner surgical site and reduces the risk of post-operative infection.
Improves bone regeneration and integration of grafts and implants with surrounding tissue.
— made entirely from your own blood.
Because it comes from your own blood, there is virtually no risk of allergic reaction or rejection.
When We Use PRF at Our Office
Our team incorporates PRF into a range of surgical procedures where enhanced healing can improve your outcome. Common applications include:
- After tooth extractions, including wisdom teeth and third molars
- Bone healing in preparation for dental implant placement
- Soft tissue and gum healing around teeth or implants
- Sinus augmentation (sinus lift) procedures
- TMJ injections to support healing in patients with certain TMD conditions
- Socket preservation after extraction
Is PRF Right for You?
Most healthy patients are good candidates for PRF therapy. Because it uses only your own blood, there is virtually no risk of rejection. PRF is particularly beneficial in these situations:
Our surgeons will discuss whether PRF is the right fit for your specific procedure and goals at your consultation.
Ready to Learn If PRF Is Right for You?
Our surgeons are happy to walk you through whether PRF makes sense for your upcoming procedure. Call us at (310) 846-8978 or schedule online.
Request an Appointment
Frequently Asked Questions
What is PRF and how is it different from PRP?
PRF (Platelet Rich Fibrin) and PRP (Platelet Rich Plasma) are both platelet concentrates derived from your own blood, but PRF is a newer generation that does not require any anticoagulants or additives. PRF produces a fibrin matrix that acts as a scaffold, allowing for a slower, sustained release of growth factors over several days. This makes PRF particularly well-suited for oral surgery and bone regeneration applications.
Is PRF safe?
Yes. Because PRF is made entirely from your own blood with no additives or chemicals, it is considered highly biocompatible. There is no risk of allergic reaction or rejection. The procedure involves only a small blood draw, the same as a standard lab test, and processing is performed chair-side during your appointment.
Will PRF speed up my recovery?
PRF can potentially support faster healing by concentrating your body’s own growth factors and placing them directly at the surgical site. Many patients report reduced swelling, less post-operative discomfort, and improved tissue healing when PRF is incorporated into their procedure. Individual results vary depending on the type of surgery, overall health, and other factors.
Does PRF cost extra?
PRF is typically an additional out-of-pocket cost that is not covered by dental insurance. Our team will discuss pricing with you during your consultation so you can make an informed decision about whether to add PRF to your procedure plan. We encourage you to ask any questions you have about costs at your appointment.
How is PRF prepared during my appointment?
A small sample of your blood is drawn just before your procedure begins. It is placed in a centrifuge, which separates the blood into layers. The fibrin-rich layer containing concentrated platelets and growth factors is extracted and prepared as a membrane, which your surgeon applies directly to the surgical site. The entire process takes only a few minutes.
Is PRF used for dental implants?
Yes. PRF is frequently used in combination with dental implant procedures and bone grafting to support bone and soft tissue regeneration at the implant site. By applying concentrated growth factors directly to the area, PRF may help improve the integration of the implant and bone graft material with the surrounding jaw bone, a critical factor in long-term implant success.
Our surgeons are happy to walk you through whether PRF makes sense for your upcoming procedure. Call us at (310) 846-8978 or schedule online.
Request an AppointmentWhat is PRF and how is it different from PRP?
PRF (Platelet Rich Fibrin) and PRP (Platelet Rich Plasma) are both platelet concentrates derived from your own blood, but PRF is a newer generation that does not require any anticoagulants or additives. PRF produces a fibrin matrix that acts as a scaffold, allowing for a slower, sustained release of growth factors over several days. This makes PRF particularly well-suited for oral surgery and bone regeneration applications.
Is PRF safe?
Yes. Because PRF is made entirely from your own blood with no additives or chemicals, it is considered highly biocompatible. There is no risk of allergic reaction or rejection. The procedure involves only a small blood draw, the same as a standard lab test, and processing is performed chair-side during your appointment.
Will PRF speed up my recovery?
PRF can potentially support faster healing by concentrating your body’s own growth factors and placing them directly at the surgical site. Many patients report reduced swelling, less post-operative discomfort, and improved tissue healing when PRF is incorporated into their procedure. Individual results vary depending on the type of surgery, overall health, and other factors.
Does PRF cost extra?
PRF is typically an additional out-of-pocket cost that is not covered by dental insurance. Our team will discuss pricing with you during your consultation so you can make an informed decision about whether to add PRF to your procedure plan. We encourage you to ask any questions you have about costs at your appointment.
How is PRF prepared during my appointment?
A small sample of your blood is drawn just before your procedure begins. It is placed in a centrifuge, which separates the blood into layers. The fibrin-rich layer containing concentrated platelets and growth factors is extracted and prepared as a membrane, which your surgeon applies directly to the surgical site. The entire process takes only a few minutes.
Is PRF used for dental implants?
Yes. PRF is frequently used in combination with dental implant procedures and bone grafting to support bone and soft tissue regeneration at the implant site. By applying concentrated growth factors directly to the area, PRF may help improve the integration of the implant and bone graft material with the surrounding jaw bone, a critical factor in long-term implant success.
Our team at Wilshire Oral Surgery and Implant Center is committed to offering advanced, evidence-based techniques that support the best possible outcomes for your oral surgical procedure. Dr. Shadi and Dr. Vahedi take the time to explain every option available to you and help you decide whether PRF is a good fit for your care plan.
If you are preparing for an extraction, bone graft, dental implant, or another oral surgical procedure, we invite you to request an appointment to speak with our surgeons about how PRF therapy may benefit your recovery.